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KMID : 0359320060460020149
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Korean Journal of Veterinary Research
2006 Volume.46 No. 2 p.149 ~ p.158
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Effects of injectable β-carotene on mastitis in dairy cows
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남향미
문진산/주이석/박용호/한홍율
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Abstract
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To determine the effects of ${eta}$-carotene on the control of mastitis in dairy cows during the dry period, 38 dairy cows (18 mastitic cows and 20 healthy cows) were administered with 5 ml of ${eta}$-carotene (30 mg/ml) intramuscularly twice (4 week intervals). Blood samples were taken from the cows before the injection and two weeks after the second injection, respectively, and were measured for the proportion of lymphocyte subpopulations and lymphocyte proliferation responses. With ${eta}$-carotene injection, the proportion of cells expressing BoCD2, BoCD4 and B and N cells increased in healthy cows. In the presence of mitogens, lymphocytes from healthy cows showed significantly higher proliferation responses after ${eta}$-carotene injection than before (p < 0.05), The somatic cell counts in ${eta}$-carotene injected group decreased from 1,001,00 cells/ml at dry off to 647,000 cell/ml and 447 cells/ml at the stage of first and second weeks after calving, respectively (p < 0,05), This study indicated that ${eta}$-carotene as a nonspecific immunostimulator could have a definite role for the prevention of intramammary infections in dairy cows at dry period.
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KEYWORD
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Cow, β-carotene, immunostimulator, mastitis
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